DEPARTMENT OF MATHEMATICS & PHYSICAL SCIENCES

Faculty

Dr. Kasia Roberts Assistant Professor Loshbaugh Hall, Room 100 918-343-7638 kroberts@rsu.edu

Education

Ph.D. Chemistry
University of Science and Technology, Gdansk, Poland
Thesis: “Products of activation and DNA adduct formation of the antitumor drug Nitracrine”
2000

M.S. Biotechnology
University of Science and Technology, Gdansk, Poland
Thesis: “The relevance of enzymatic oxidation to antitumor potency of imidazoacridinone derivatives”
1994

Professional Experience

2008-present, Assistant Professor of Chemistry
Rogerst State University, Claremore, OK

2003-2008, Instructor of Organic and General Chemistry
Tulsa Community College, Tulsa, OK

2000-2002, Postdoctoral Fellowship
National Center for Toxicological Research, Food and Drug Administration

1995-1999, Teaching Assistant for Biochemistry and Cell Biology
University of Science and Technology, Gdansk, Poland

Research and Scholarship

• Principal investigator of a research grant on “Metabolism of nitroaromatic compounds of antitumor potency.” University of Science and Technology, Gdansk, Poland
• Research Fellowships:
  • National Center for Toxicological Research, Jefferson, AR, USA March-August 1998
  • Ames Laboratory, Iowa State University, Ames, IA, USA  April-July 1999
• Conducted research on the metabolism and mechanism of action of DNA-reacting compounds (nitroacridinone, heterocyclic and aromatic amines) heterocyclic and aromatic amine DNA adducts syntheses, identification of DNA adducts from epithelial cells of human breast, polymorphism of carcinogen activating enzymes in relevance to breast carcinogenesis, bioremediation of hydrocarbons in soil and gasoline additives in water reservoirs.

Publications

Ph.D Thesis: “Products of activation and DNA adduct formation of the antitumor drug Nitracrine”, Gdansk University of Science and Technology, Gdansk, Poland 1994

M.Sc. Thesis: “The relevance of enzymatic oxidation to antitumor potency of imidazoacridinone derivatives”, Gdansk University of Science and Technology, Gdansk, Poland 2000

Ambrosone Christine, Abrams Sara, Gorlewska-Roberts Katarzyna, and Kadlubar Fred, Hair Dye Use, Meat Intake, and Tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells, Archives of Biochemistry and Biophysics, 464, 169-175, 2007

Gorlewska-Roberts Katarzyna, Teitel Candee, Lay Jackson,  Roberts Dean, and Kadlubar Fred, Lactoperoxidase-catalyzed activation of carcinogenic aromatic and heterocyclic amines, Chemical Research in Toxicology, 17, 1659-1666, 2004

Gorlewska-Roberts Katarzyna, Wiese Frederick W., and Kadlubar Fred F. Recent advances in our understanding of the role of peroxidases in human carcinogenesis, Molecular and Therapeutic Aspects of Redox Biochemistry, OICA International UK, 2003

Gorlewska-Roberts Katarzyna, Green Bridgette, Fares Manal, Ambrosone Christine, and Kadlubar Fred. Carcinogen-DNA adducts in human breast epithelial cells Environmental and Molecular Mutagenesis, 39, 184-192, 2002

Gorlewska Katarzyna, Mazerska Zofia, Sowinski Pawel, Konopa Jerzy. Products of activation of the antitumor drug Ledakrin (Nitracrine) in vitro. Chemical Research in Toxicology, 14, (1), 1-10, 2001

Mazerska Zofia , Gorlewska Katarzyna, Kraciuk Agnieszka, Konopa Jerzy. The relevance of enzymatic oxidation by horseradish peroxidase to antitumor potency of imidazoacridinone derivatives. Chemico.-Biological Interactions, 115, 1-22, 1998

Gorlewska Katarzyna, Mazerska Zofia, Konopa Jerzy. Metabolic activation pathway of antitumor drug Ledakrin (Nitracrine). Studies with the use of model system. Experimental and Toxicol. Pathol., 48, suppl. II, 155-160, 1996

Gorlewska Katarzyna, Teitel Candee, Kadlubar Fred F. The role of lactoperoxidase-catalyzed activation of aromatic and heterocyclic amines in breast cancer. American Association for Cancer Research Annual Meeting, New Orleans, March 2001, abstarct no. 4800

Gorlewska Katarzyna, King Roberta, Mazerska Zofia, Konopa Jerzy, Kadlubar Fred. Metabolic activation and DNA-adduct formation by the anticancer drug Nitracrine. American Association for Cancer Research Annual Meeting, Philadelphia, April 1999, abstract no. 31

Gorlewska Katarzyna, Mazerska Zofia, Konopa Jerzy. Study on metabolic activation of antitumor active imidazoacridinone  derivatives. 5th International Symposium on Molecular Aspects of Chemotherapy, Gdansk, August 1995, abstract no. 17

Gorlewska Katarzyna and Konopa Jerzy, International workshop on drug metabolism, Copenhagen, Denmark, June 1998, abstract no. 46