Department of Biology

Dr. Jin Seo

Dr. Jin Seo

Assistant Professor
Loshbaugh Hall, Room 208



Ph.D., Microbiology
University of Texas at Austin

M.S., Interdisciplinary Program of Genetic Engineering
Seoul National University, Seoul, Korea

B.S., Biochemistry
Yonsei University, Seoul, Korea

Professional Experience

2013-Present, Assistant Professor, Department of Biology
Rogers State University, Claremore, OK

2009-2013, Adjunct Instructor
Richland College, Dallas, TX

2013, Instructor, Department of Plastic Surgery
2011-2012, Instructor, Department of Developmental Biology
2005-2011, Postdoctoral Fellow, Department of Developmental Biology
UT Southwestern Medical Center, Dallas, TX

1998-2005, Graduate Research Assistant, Department of Microbiology
University of Texas at Austin

1998, Research Fellow
Samsung Biomedical Research Center, Seoul, Korea

1992-1993, Exchange Student
University of Illinois, Urbana-Champaign, IL

Courses Taught:

  • Anatomy and Physiology (BIOL-2215)
  • General Cellular Biology (BIOL-1144)
  • Microbiology (BIOL-2124)
  • Molecular Cell Biology (BIOL-3503)

Research Interests

My research interests are cellular and molecular mechanisms to regulate obesity and diabetes. I have mainly focused on two signaling pathways in fat tissue: the Wnt pathway and the endoplasmic reticulum (ER) stress pathway that control adipocyte differentiation, energy expenditure, and insulin sensitivity. There are research opportunities for students who are interested in the cellular and molecular biology research.


  • 2013, Stenesen, D., Suh, J.M., Seo, J., Yu, K., Lee, K.S., Kim, J.S., Min, K.J., Graff, J.M., Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies. Cell Metab. 17:101-112
  • 2012, Zeve, D*., Seo, J.*, Suh, JM*., Stenesen, D., Tang, W., Berglund, E., Wan, Y., Williams, L., Lim, A., Martinez, M., Mckay, R., Millay, D., Olson, E., Graff, J. M., Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake. Cell Metab.15:492-504 (* Equal Contribution)
  • 2011, Tang, W., Zeve, D., Seo, J., Jo, A., Graff, J. M. Thiazolidinediones regulate adipose lineage dynamics. Cell Metab. 14:116-22
  • 2009, Seo, J., Fortuno III, E., Suh, J.M., Stenesen, D., Tang, W., Townes, T., Parks, E., Adams, C.M., Graff, J.M. Atf4 regulates obesity, glucose homeostasis and energy expenditure. Diabetes, 58:2565-73
  • 2009, Yoshizawa, T., Hinoi, E., Jung, D., Kajimura, D., Ferron, M., Seo, J., Graff, J.M., Kim, J., and Karsenty, G. The transcription factor Atf4 regulates glucose metabolism through its expression in osteoblasts, J. Clin. Invest. 119:2807-17
  • 2007, Suh, J.M., Zeve, D., McKay, R., Seo, J., Salo, Z., Li R., Wang, M., and Graff, J. M. Adipose is a conserved dosage-sensitive anti-obesity gene. Cell Metab. 6(3): 195-207
  • 2006, Maitra, U., Seo J., Lozano, M., Dudley, J. Differentiation-induced cleavage of Cutl1/CDP generates a novel dominant-negative isoform that regulates mammary gene expression.  Mol. Cell. Biol. 26(20): 7466-7478
  • 2005, Seo, J., Lozano, M., Dudley, J. Nuclear matrix binding regulates SATB1-mediated transcriptional repression. J. Biol Chem 280(26): 24600-24609
  • 1997, Seo, J., Kim, S.N., Lee, G. R., Kim, S. Y., Park, S. D., Hong, S.H.  Growth inhibition of human ovarian cancer cells by differential modulation of protein kinase A isozymes, Korean J. Biol. Sci. 1: 389-394
  • 1995, Seo, J., Kim, J.S., Hwang, E. S., Lee, J.H., Hong, S.W. Endogenous gene expression of p53 and regulatory subunits of cyclic AMP-dependent protein kinase in ovarian cancer cells, Korean J. Zool. 38: 204-211

Invited talks           

  • 2010, Adipose-specific activation of -catenin improves glucose metabolism, 8th International Diabetes Federation Western Pacific Region Congress, Busan, Korea
  • 2008, Atf4 mutant mice are lean, Workshop on the establishment, maintenance, and turnover of fat depots, National Institute of Health (NIH), Bethesda, MD          

Research Supports       

  • 2013-2014, Obesity Control by two Cellular Metabolic Pathways, the UPR and mTOR pathways, Role: PI
    Rogers State University Organized Research Grant
  • 2009-2011, Effects of Atf4 on Obesity and its Sequelae, Role: PI
    American Heart Association (AHA) Postdoctoral Fellowship (# 09POST2080348)

Awards and Honors

  • 2008, Abstract Hot Topic Award, National Institutes of Health (NIH)
  • 2001, The Lois Sager-Foxhall Memorial Scholarship Award, University of Texas at Austin
  • 1993, Academic Scholarship Award, Seoul National University, Seoul, Korea
  • 1989, Academic Scholarship Award, Yonsei University, Seoul, Korea
  • 1989, Dean's Award for Academic Excellence, Yonsei University, Seoul, Korea

Peer Review Activities  

  • 2012, Journal reviewer for Cell Research